Acylcarnitine C12-OH Unit Converter
Convert between µmol/L, nmol/mL
Also known as: 3-Hydroxydodecanoylcarnitine, 3-Hydroxylauroylcarnitine, 3-OH-Dodecanoylcarnitine, C12-OH
Convert Acylcarnitine C12-OH
What is Acylcarnitine C12-OH?
Acylcarnitine C12-OH (3-hydroxydodecanoylcarnitine) is a hydroxylated medium-chain acylcarnitine. It forms when a 12-carbon fatty acid with a hydroxyl group is attached to carnitine during mitochondrial fatty acid breakdown.
It is a normal intermediate of mitochondrial beta-oxidation, specifically generated during the hydration step of the fatty acid oxidation spiral. Under normal conditions, C12-OH is rapidly processed and does not accumulate in significant amounts.
When enzymes responsible for processing hydroxylated fatty acid intermediates are impaired, C12-OH can accumulate in the blood. It is measured alongside other acylcarnitines as part of a comprehensive acylcarnitine profile to help identify fatty acid oxidation disorders.
Where Does Acylcarnitine C12-OH Come From?
C12-OH is produced inside mitochondria during the beta-oxidation of medium- to long-chain fatty acids. It is generated primarily in tissues with high energy demands, including the liver, skeletal muscle, and heart.
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