Acylcarnitine C14:1-OH Unit Converter

Acylcarnitine C14:1-OH (3-hydroxytetradecenoylcarnitine) is a hydroxylated long-chain acylcarnitine found in the blood. It forms when a 14-carbon, monounsaturated, hydroxylated fatty acid intermediate binds to carnitine during mitochondrial fat metabolism.

Carnitine acts as a shuttle, carrying fatty acid fragments into and out of mitochondria so they can be broken down for energy. When a step in this breakdown process is impaired, specific acylcarnitine species accumulate in the blood.

C14:1-OH is measured as part of a full acylcarnitine profile and is typically present in very low concentrations in healthy individuals. Elevated levels may point to disorders of long-chain fatty acid oxidation or mitochondrial dysfunction.

C14:1-OH is produced inside mitochondria when long-chain fatty acids undergo beta-oxidation. It forms as carnitine conjugates with a hydroxylated 14-carbon intermediate, primarily in tissues with high fatty acid oxidation activity such as the liver, heart, and skeletal muscle.