Estradiol, Urine Creatinine Ratio Unit Converter

Estradiol (E2) is the most potent and biologically active form of estrogen. It plays a central role in reproductive health, bone maintenance, cardiovascular function, and brain health.

This marker measures estradiol in a urine sample, divided by urinary creatinine concentration to correct for urine dilution. The ratio approximates what a full 24-hour urine collection would show from a single convenient spot sample.

Urine testing captures integrated hormone output over time rather than a single-point snapshot, making it useful for hormones with pulsatile or cyclical secretion patterns. Results are typically reported in ng/mg creatinine.

Produced primarily in the ovaries (women) and testes (men) via aromatase conversion of testosterone. Adipose tissue, the adrenal glands, brain, and bone also produce estradiol locally through peripheral aromatization of androgens.